Dietary interventions for managing glucose abnormalities in cystic fibrosis: a systematic review protocol.

ABSTRACT:

Background

Glucose abnormalities in cystic fibrosis (CF) are common, but there is limited evidence to guide their dietary management. Progressive impaired glucose tolerance eventually leads to cystic fibrosis-related diabetes (CFRD), the most prevalent complication of CF, which is associated with increased morbidity and mortality. Optimising glycaemic control improves clinical status and reduces mortality; insulin therapy is the primary means of controlling glycaemia in CFRD, but its role in managing pre-diabetes is less clear. CF dietary therapy requires a high calorie diet due to increased energy expenditure and malabsorption, but this energy-dense diet is typically high in fat and sugar, and high sugar intakes often result in hyperglycaemia in individuals who have impaired gluco

SUBMITTER: Birch L 

PROVIDER: S-EPMC6052510 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature