Polypharmacy in older patients with chronic diseases: a cross-sectional analysis of factors associated with excessive polypharmacy.

ABSTRACT:

Background

Polypharmacy is common in older people and associated with potential harms. The aim of this study was to analyse the characteristics of an older multimorbid population with polypharmacy and to identify factors contributing to excessive polypharmacy in these patients.

Methods

This cross-sectional analysis is based on the PRIMA-eDS trial, a large randomised controlled multicentre study of polypharmacy in primary care. Patients' baseline data were used for analysis. A number of socioeconomic and medical data as well as SF-12-scores were entered into a generalized linear mixed model to identify variables associated with excessive polypharmacy (taking ≥10 substances daily).

Results

Three thousand nine hundred four participants were recruited. Risk factors signif

SUBMITTER: Rieckert A 

PROVIDER: S-EPMC6052592 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature