Assessment of a renal angina index for prediction of severe acute kidney injury in critically ill children: a multicentre, multinational, prospective observational study.

ABSTRACT:

Background

Acute kidney injury (AKI) occurs in one in four children admitted to the intensive care unit (ICU) and AKI severity is independently associated with increased patient morbidity and mortality. Early prediction of AKI has the potential to improve outcomes. In smaller, single center populations, we have previously derived and validated the performance of the renal angina index (RAI), a context driven risk stratification system, to predict severe AKI.

Methods

A prospective, observational study (AWARE¹, January-December 2014) was conducted in intensive care units from 32 centers in 9 countries. The primary outcome was the presence of severe AKI ("AKI_S"; Stage 2-3 AKI KDIGO guidelines) on the third day after ICU admission (). We compared the perfor

SUBMITTER: Basu RK 

PROVIDER: S-EPMC6053052 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature