Heavy Metal Exposure and Metabolic Syndrome: Evidence from Human and Model System Studies.

ABSTRACT:

Purpose of review

Metabolic syndrome (MS) describes the co-occurrence of conditions that increase one's risk for heart disease and other disorders such as diabetes and stroke. The worldwide increase in the prevalence of MS cannot be fully explained by lifestyle factors such as sedentary behavior and caloric intake alone. Environmental exposures, such as heavy metals, have been implicated, but results are conflicting and possible mechanisms remain unclear. To assess recent progress in determining a possible role between heavy metal exposure and MS, we reviewed epidemiological and model system data for cadmium (Cd), lead (Pb), and mercury (Hg) from the last decade.

Recent findings

Data from 36 epidemiological studies involving 17 unique countries/regions and 13 studies leverag

SUBMITTER: Planchart A 

PROVIDER: S-EPMC6053628 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature