The association of depression and all-cause and cause-specific mortality: an umbrella review of systematic reviews and meta-analyses.

ABSTRACT:

Background

Depression is a prevalent and disabling mental disorder that frequently co-occurs with a wide range of chronic conditions. Evidence has suggested that depression could be associated with excess all-cause mortality across different settings and populations, although the causality of these associations remains unclear.

Methods

We conducted an umbrella review of systematic reviews and meta-analyses of observational studies. PubMed, PsycINFO, and Embase electronic databases were searched through January 20, 2018. Systematic reviews and meta-analyses that investigated associations of depression and all-cause and cause-specific mortality were selected for the review. The evidence was graded as convincing, highly suggestive, suggestive, or weak based on quantitative crit

SUBMITTER: Machado MO 

PROVIDER: S-EPMC6053830 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature