Potential impact of influenza vaccine roll-out on antibiotic use in Africa.

ABSTRACT: Background:Influenza infections result in both inappropriate and appropriate antibiotic prescribing. There is a huge burden of both influenza and infections caused by antimicrobial-resistant pathogens in Africa. Influenza vaccines have the potential to reduce appropriate antibiotic use, through reduction of secondary bacterial infections, as well as to reduce levels of influenza misdiagnosed and treated as a bacterial infection (inappropriate). Objectives:To estimate potential reductions in antibiotic use that are achievable by introducing an influenza vaccine into various African settings. Methods:Influenza incidence was combined with population size, vaccine and health system characteristics. Results:We estimated that the direct impact of vaccination could avert more than 390 prescriptio

SUBMITTER: Knight GM 

PROVIDER: S-EPMC6054263 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature