Frontoparietal processing of stress-relevant information differs in individuals with a negative cognitive style.

ABSTRACT: Prior research indicates that cognitive vulnerabilities can render individuals more susceptible to psychopathology in the wake of stressful events. However, little work has directly targeted the neural mechanisms involved. In this study, we examined functional magnetic resonance imaging (fMRI) activity as a function of negative cognitive style, a well-studied cognitive vulnerability for depression. We adapted a robust paradigm in which undergraduate students completed fMRI testing after a known ecologically valid stressor (a midterm exam). Negative cognitive style correlated with brain activity in response to both negative and exam-related information in dorsolateral prefrontal cortex and/or angular gyrus, both regions involved in abstract, self-referential thought. There were commonalitie

SUBMITTER: Westbrook C 

PROVIDER: S-EPMC6054475 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature