Molecularly selective nanoporous membrane-based wearable organic electrochemical device for noninvasive cortisol sensing.

ABSTRACT: Wearable biosensors have emerged as an alternative evolutionary development in the field of healthcare technology due to their potential to change conventional medical diagnostics and health monitoring. However, a number of critical technological challenges including selectivity, stability of (bio)recognition, efficient sample handling, invasiveness, and mechanical compliance to increase user comfort must still be overcome to successfully bring devices closer to commercial applications. We introduce the integration of an electrochemical transistor and a tailor-made synthetic and biomimetic polymeric membrane, which acts as a molecular memory layer facilitating the stable and selective molecular recognition of the human stress hormone cortisol. The sensor and a laser-patterned microcapillar

SUBMITTER: Parlak O 

PROVIDER: S-EPMC6054510 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature