A prospective study of cancer survivors and risk of sepsis within the REGARDS cohort.

ABSTRACT:

Background

Hospitalized cancer patients are nearly 10 times more likely to develop sepsis when compared to patients with no cancer history. We compared the risk of sepsis between cancer survivors and no cancer history participants, and examined whether race was an effect modifier.

Methods

We performed a prospective analysis of data from the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. We categorized participants as "cancer survivors" or "no cancer history" derived from self-reported responses of being diagnosed with any cancer, excluding non-melanoma skin cancer. We defined sepsis as hospitalization for a serious infection with ≥2 systemic inflammatory response syndrome criteria. We performed Cox proportional hazard models to examine the risk of

SUBMITTER: Moore JX 

PROVIDER: S-EPMC6054880 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature