Association between statin drug use and peripheral blood leukocyte telomere length in the National Health and Nutrition Examination Survey 1999-2002: a cross-sectional study.

ABSTRACT:

Purpose

To evaluate the association between statin drug use and peripheral blood leukocyte telomere length in a U.S. nationally representative sample of adults.

Methods

We conducted a cross-sectional analysis of data from National Health and Nutrition Examination Survey 1999-2002, representative of the noninstitutionalized U.S.

Population

The analytic study population included 3496 men and women aged 40-84 years without a history of cancer and who had information of telomere length and statin use.

Results

Compared with nonusers, statin users were more likely to be former smokers, older, white, male, and had more comorbidities. Statin users did not have longer telomeres than nonusers after age (coefficient -0.013, p = .30) and multivariable (0.0003, p = .98) adj

SUBMITTER: Tran PT 

PROVIDER: S-EPMC6054912 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature