Blood Gene Expression and Vascular Function Biomarkers in Professional Saturation Diving.

ABSTRACT: Saturation diving is an established way to conduct subsea operations with human intervention. While working, the divers must acclimatize to the hyperbaric environments. In this study, genome-wide gene expression and selected plasma biomarkers for vascular function were investigated. We also examined whether antioxidant vitamin supplements affected the outcome. The study included 20 male professional divers, 13 of whom took vitamin C and E supplements in doses of 1,000 and 30 mg daily during saturation periods that lasted 7-14 days. The dives were done in a heliox atmosphere with 40 kPa oxygen partial pressure (ppO₂) to a depth of 100-115 m of sea-water (msw), from which the divers performed in-water work excursions to a maximum depth of 125 msw with 60 kPa ppO₂. Venou

SUBMITTER: Kiboub FZ 

PROVIDER: S-EPMC6054983 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature