The association between red cell distribution width and venous thromboembolism is not explained by myocardial infarction, stroke, or cancer.

ABSTRACT:

Background

Red cell distribution width (RDW) is a risk marker of venous thromboembolism (VTE), myocardial infarction (MI), stroke, and cancer. Due to interrelations between these diseases, the association between RDW and VTE may be explained by MI, stroke, or cancer.

Objective

To investigate whether the effect of RDW on VTE could be explained by intermediate development of MI, stroke, or cancer.

Methods

RDW was measured in 24 363 participants of the Tromsø Study in 1994-1995. Incident VTE, MI, stroke, and cancer were registered until December 31, 2010. Conventional and cause-specific Cox-regression models were used to estimate hazard ratios (HR) for VTE with 95% confidence intervals (CI) across categories of RDW.

Results

There were 502 first VTEs during a media

SUBMITTER: Ellingsen TS 

PROVIDER: S-EPMC6055489 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature