Acute infection as a trigger for incident venous thromboembolism: Results from a population-based case-crossover study.

ABSTRACT:

Background

A bidirectional relation exists between acute infection and immobilization, and both are triggers for venous thromboembolism (VTE). To what extent the association between infection and VTE-risk is explained by immobilization is unknown.

Aims

To investigate the impact of hospitalization with acute infection on the VTE-risk in patients with and without concomitant immobilization, and to explore the differential impact of respiratory- (RTI) and urinary- (UTI) tract infections on the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE).

Methods

We conducted a case-crossover study of VTE-patients (n = 707) recruited from a general population. Hospitalizations and VTE-triggers were registered during the 90 days before a VTE (hazard period) and in four p

SUBMITTER: Grimnes G 

PROVIDER: S-EPMC6055491 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature