Factors associated with the efficacy of smoking cessation treatments and predictors of smoking abstinence in EAGLES.

ABSTRACT:

Aims

To assess (1) how far the efficacies of front-line smoking cessation pharmacotherapies vary as a function of smoker characteristics and (2) associations between these characteristics and success of smoking cessation attempts.

Design

Prospective correlational study in the context of a double-blind randomized trial. The outcome was regressed individually onto each covariate after adjusting for treatment, and then a forward stepwise model constructed. Treatment moderator effects of covariates were tested by treatment × covariate interactions.

Setting

Health service facilities in multiple countries.

Participants

Data came from 8120 smokers willing to make a quit attempt, randomized to varenicline, bupropion, nicotine replacement therapy (NRT) or placebo in Eva

SUBMITTER: West R 

PROVIDER: S-EPMC6055735 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature