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Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab.


ABSTRACT: Patients receiving eculizumab have an increased risk for meningococcal disease, but most reported cases are attributable to encapsulated meningococcal strains. We describe a case in which a nongroupable meningococcal strain, which rarely causes disease in healthy persons, caused fatal disease in an eculizumab recipient despite meningococcal vaccination.

SUBMITTER: Nolfi-Donegan D 

PROVIDER: S-EPMC6056112 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature