Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab.
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ABSTRACT:
SUBMITTER: Nolfi-Donegan D
PROVIDER: S-EPMC6056112 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Publications
Fatal Nongroupable Neisseria meningitidis Disease in Vaccinated Patient Receiving Eculizumab.
Nolfi-Donegan Deirdre D Konar Monica M Vianzon Vianca V MacNeil Jessica J Cooper James J Lurie Perrianne P Sedivy Judi J Wang Xin X Granoff Dan M DM McNamara Lucy L
Emerging infectious diseases 20180801 8
Patients receiving eculizumab have an increased risk for meningococcal disease, but most reported cases are attributable to encapsulated meningococcal strains. We describe a case in which a nongroupable meningococcal strain, which rarely causes disease in healthy persons, caused fatal disease in an eculizumab recipient despite meningococcal vaccination. ...[more]
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