Prediagnosis Use of Statins Associates With Increased Survival Times of Patients With Pancreatic Cancer.

ABSTRACT:

Background & aims

Statin medications, most commonly prescribed to reduce lipid levels and prevent cardiovascular disease, may be associated with longer survival times of patients with cancer. However, the association of statins with outcomes of patients with pancreatic adenocarcinoma is not clear.

Methods

We analyzed the association of statin use before a diagnosis of pancreatic cancer with survival times of 648 participants in the Nurses' Health Study and Health Professionals Follow-up Study who were diagnosed with pancreatic adenocarcinoma from 2000 through 2013. We estimated hazard ratios (HRs) for overall mortality using Cox proportional hazards models with adjustment for potential confounders. We assessed the temporal association between prediagnosis statin use and canc

SUBMITTER: Hamada T 

PROVIDER: S-EPMC6056316 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature