Synthesis, Structure, DNA Interaction, and SOD Activity of Three Nickel(II) Complexes Containing L-Phenylalanine Schiff Base and 1,10-Phenanthroline.

ABSTRACT: Three hexacoordinated octahedral nickel(II) complexes, [Ni(sal-L-phe)(phen)(CH₃OH)]·CH₃OH (1), [Ni(naph-L-phe)(phen)(CH₃OH)] (2), and [Ni(o-van-L-phe)(phen)(CH₃OH)]·5CH₃OH (3) (sal-L-phe = a Schiff base derived from salicylaldehyde and L-phenylalanine, naph-L-phe = a Schiff base derived from 2-hydroxy-1-naphthaldehyde and L-phenylalanine, o-van-L-phe = a Schiff base derived from o-vanillin and L-phenylalanine, and phen = 1,10-phenanthroline), have been synthesized and characterized by elemental analysis, IR spectra, and single-crystal X-ray diffraction. The interactions of these complexes with CT-DNA were studied by UV-Vis absorption spectroscopy, fluorescence spectroscopy, circular dichroism s

SUBMITTER: Zhao P 

PROVIDER: S-EPMC6057355 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature