Age-related dataset on the mechanical properties and collagen fibril structure of tendons from a murine model.

ABSTRACT: Connective tissues such as tendon, ligament and skin are biological fibre composites comprising collagen fibrils reinforcing the weak proteoglycan-rich ground substance in extracellular matrix (ECM). One of the hallmarks of ageing of connective tissues is the progressive and irreversible change in the tissue mechanical properties; this is often attributed to the underlying changes to the collagen fibril structure. This dataset represents a comprehensive screen of the mechanical properties and collagen fibril structure of tendon from the tails of young to old (i.e. 1.6-35.3 month-old) C57BL6/B mice. The mechanical portion consists of the load-displacement data, as well as the derived tensile properties; the structure data consists of transmission electron micrographs of collagen fibril cros

SUBMITTER: Goh KL 

PROVIDER: S-EPMC6057439 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature