Changes in Blood Pressure During Young Adulthood and Subsequent Kidney Function Decline: Findings From the Coronary Artery Risk Development in Young Adulthood (CARDIA) Study.

ABSTRACT:

Background

Many studies have focused on the association between a single blood pressure (BP) measurement and risk for adverse outcomes. However, the association of BP trajectories during young adulthood with subsequent decline in kidney function has not been well defined.

Study design

Observational cohort study.

Setting & participants

3,429 participants in the Coronary Artery Risk Development in Young Adulthood (CARDIA) Study enrolled between the ages of 18 and 30 years.

Predictors

BP slope during the first 10 years of participation in CARDIA, derived from linear mixed models incorporating all repeated BP measures.

Outcome

Decline in estimated glomerular filtration rate (eGFR) during the interval between years 10 and 20 of CARDIA participation using cyst

SUBMITTER: Ku E 

PROVIDER: S-EPMC6057820 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature