Ontology highlight
ABSTRACT:
SUBMITTER: Wang P
PROVIDER: S-EPMC6057964 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Wang Peiyuan P Fan Yong Y Lu Lingfei L Liu Lu L Fan Lingling L Zhao Mengyao M Xie Yang Y Xu Congjian C Zhang Fan F
Nature communications 20180724 1
Local recurrence is a common cause of treatment failure for patients with solid tumors. Tumor-specific intraoperative fluorescence imaging may improve staging and debulking efforts in cytoreductive surgery and, thereby improve prognosis. Here, we report in vivo assembly of the second near-infrared window (NIR-II) emitting downconversion nanoparticles (DCNPs) modified with DNA and targeting peptides to improve the image-guided surgery for metastatic ovarian cancer. The NIR-II imaging quality with ...[more]