Clinical outcomes during anticoagulant therapy in fragile patients with venous thromboembolism.

ABSTRACT:

Background

Subgroup analyses from randomized trials suggested favorable results for the direct oral anticoagulants in fragile patients with venous thromboembolism (VTE). The frequency and natural history of fragile patients with VTE have not been studied yet.

Objectives

To compare the clinical characteristics, treatment and outcomes during the first 3 months of anticoagulation in fragile vs non-fragile patients with VTE.

Methods

Retrospective study using consecutive patients enrolled in the RIETE (Registro Informatizado Enfermedad TromboEmbolica) registry. Fragile patients were defined as those having age ≥75 years, creatinine clearance (CrCl) levels ≤50 mL/min, and/or body weight ≤50 kg.

Results

From January 2013 to October 2016, 15 079 patients were recruited

SUBMITTER: Moustafa F 

PROVIDER: S-EPMC6058265 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature