Ethanol locks for the prevention of catheter-related bloodstream infection: a meta-analysis of randomized control trials.

ABSTRACT:

Background

Current evidence regarding the efficacy of ethanol locks in preventing catheter-related bloodstream infection (CRBI) is inconclusive.

Methods

Electronic databases, including PubMed, Web of Science, Embase, and the Cochrane Library (until April 2018),were systematically searched for relevant studies. Two reviewers independently screened the retrieved records and identified RCTs that met the inclusion criteria. Relevant data were extracted for pooled analyses using Review Manager 5.3 software. Subgroup analysis was performed according to the study quality, duration of the ethanol lock, disease type and CRBI definition. Eggs' method was applied to detect publication bias. Sensitivity analysis was conducted to check the stability of the meta-analysis results.

Resul

SUBMITTER: Zhang P 

PROVIDER: S-EPMC6058389 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature