Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma.

ABSTRACT: The 2014 Surgeon General's Report on smoking and health concluded that changing cigarette designs have caused an increase in lung adenocarcinomas, implicating cigarette filter ventilation that lowers smoking machine tar yields. The Food and Drug Administration (FDA) now has the authority to regulate cigarette design if doing so would improve public health. To support a potential regulatory action, two weight-of-evidence reviews were applied for causally relating filter ventilation to lung adenocarcinoma. Published scientific literature (3284 citations) and internal tobacco company documents contributed to causation analysis evidence blocks and the identification of research gaps. Filter ventilation was adopted in the mid-1960s and was initially equated with making a cigarette safer. Since

SUBMITTER: Song MA 

PROVIDER: S-EPMC6059254 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature