Ontology highlight
ABSTRACT: Background
The lack of effective therapies for heart failure with preserved ejection fraction (HFpEF) reflects an incomplete understanding of its pathogenesis.Design
We analysed baseline risk factors for incident HFpEF, heart failure with reduced ejection fraction (HFrEF) and valvular heart failure (VHF) in a community-based cohort.Methods
We recruited 2101 men and 1746 women ≥60 years of age with hypertension, diabetes, ischaemic heart disease (IHD), abnormal heart rhythm, cerebrovascular disease or renal impairment. Exclusion criteria were known heart failure, left ventricular ejection fraction <50% or valve abnormality >mild in severity. Median follow-up was 5.6 (IQR 4.6-6.3) years.Results
Median time to heart failure diagnosis in 162 participants was 4.5
SUBMITTER: Gong FF
PROVIDER: S-EPMC6059280 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature