GP-OSMOTIC trial protocol: an individually randomised controlled trial to determine the effect of retrospective continuous glucose monitoring (r-CGM) on HbA1c in adults with type 2 diabetes in general practice.

ABSTRACT:

Introduction

Optimal glycaemia can reduce type 2 diabetes (T2D) complications. Observing retrospective continuous glucose monitoring (r-CGM) patterns may prompt therapeutic changes but evidence for r-CGM use in T2D is limited. We describe the protocol for a randomised controlled trial (RCT) examining intermittent r-CGM use (up to 14 days every three months) in T2D in general practice (GP).

Methods and analysis

General Practice Optimising Structured MOnitoring To achieve Improved Clinical Outcomes is a two-arm RCT asking 'does intermittent r-CGM in adults with T2D in primary care improve HbA1c?'

Primary outcome

Absolute difference in mean HbA1c at 12 months follow-up between intervention and control arms.

Secondary outcomes

(a) r-CGM per cent time in target (4-1

SUBMITTER: Furler J 

PROVIDER: S-EPMC6059310 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature