Women undergoing assisted fertilisation and high-intensity interval training: a pilot randomised controlled trial.

ABSTRACT:

Objectives

Overweight and obese women often seek assisted fertilisation. In the obese population, pregnancy rates are 30%-75% below that of normal weight women who undergo assisted fertilisation. We hypothesised that high-intensity interval training (HIT) would improve fertility by improving insulin sensitivity and thus affect the hypothalamic-pituitary-ovarian axis and ovarian androgen production. Our aim was to assess whether HIT prior to assisted fertilisation would increase pregnancy rate.

Methods

Eighteen overweight and obese women (body mass index>25.0 kg/m²) were randomised to HIT (n=8) or usual care (control, n=10) before assisted fertilisation. HIT was undertaken three times weekly for 10 weeks; two sessions of 4×4 min HIT and one session of 10×1 min HIT.

SUBMITTER: Kiel IA 

PROVIDER: S-EPMC6059324 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature