Subclinical and clinical chorioamnionitis, fetal vasculitis, and risk for preterm birth: A cohort study.

ABSTRACT:

Objective

To evaluate the association between subclinical and clinical chorioamnionitis and risk of preterm birth (PTB).

Methods

Demographic and clinical characteristics were abstracted from medical records and placental examinations performed (N = 1371 pregnancies including spontaneous and medically-indicated PTBs). Pregnancies were classified as having clinical chorioamnionitis (with or without histologic chorioamnionitis), subclinical chorioamnionitis (histologic, but not clinical, chorioamnionitis), or no chorioamnionitis; pregnancies with histologic chorioamnionitis were further evaluated for fetal vasculitis. Relative risks for PTB, early and late PTB, and PTB ± premature rupture of membranes (PROM) were adjusted for maternal characteristics.

Results

Clinical (4

SUBMITTER: Palmsten K 

PROVIDER: S-EPMC6059374 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature