Impact of mediastinal lymph node enlargement on the prognosis of idiopathic pulmonary fibrosis.

ABSTRACT:

Background

Mediastinal lymph node enlargement (LNE) is common in idiopathic pulmonary fibrosis (IPF) and is known to be associated with the severity of lung fibrosis. However, the relationship between mediastinal LNE and the prognosis of IPF has not been determined to date.

Methods

This study included patients with IPF from the interstitial lung disease registry at Seoul National University Bundang Hospital, from January 2012 to March 2016. Two thoracic radiologists independently reviewed mediastinal LNE and lung parenchymal fibrosis and ground glass opacities in chest computed tomography scans of each patient, which were obtained upon diagnosis. Mortality and admission rates were analyzed.

Results

In total, 132 patients (104 [78.8%] male; median age, 72 years; range,

SUBMITTER: Sin S 

PROVIDER: S-EPMC6059471 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature