Nutraceuticals in prostate cancer therapeutic strategies and their neo-adjuvant use in diverse populations.

ABSTRACT: Prostate cancer (PCa) is the most frequently diagnosed malignancy and second leading cause of cancer mortality in American males. Notably, men of African descent in the United States and Caribbean have the highest PCa mortality rates compared to men with European ancestry. Although current therapeutics are quite potent and effective, disease resistance, progression to metastasis, therapy-associated toxicities and efficacy-related issues in diverse populations develop over time. Thus, non-toxic and efficacious therapeutic strategies are needed to address these major obstacles for the clinical treatment and management of PCa. In this regard, preclinical and population-based efficacy studies have shown the potential of natural non-toxic nutraceuticals as potent anti-PCa agents. Accordingly, t

SUBMITTER: Reed D 

PROVIDER: S-EPMC6060229 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature