Sinonasal aspergillosis: Outcome after topical treatment in dogs with cribriform plate lysis.

ABSTRACT:

Background

Cribriform lysis has been considered a contraindication for topical treatment of sinonasal aspergillosis (SNA) because of concerns about drug extravasation with resultant neurologic signs or death.

Objective/hypothesis

To describe dogs with SNA and cribriform plate lysis treated with topical antifungal medications. Our hypothesis was that the conventional dogma that topical therapy should be avoided in these cases is incorrect.

Animals

Nine client-owned dogs with SNA and lysis of the cribriform plate, lysis of the floor of a frontal sinus or both detected by computed tomography (CT).

Methods

A retrospective review of medical records was performed. Dogs that met inclusion criteria (ie, SNA confirmed by at least 1 laboratory test, braincase affected on

SUBMITTER: Belda B 

PROVIDER: S-EPMC6060319 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature