Antigenic and genetic characterization of influenza viruses isolated in Mozambique during the 2015 season.

ABSTRACT:

Background

Due to the high rate of antigenic variation of influenza virus, seasonal characterization of the virus is crucial to assess and monitor the emergence of new pathogenic variants and hence formulate effective control measures. However, no study has yet been conducted in Mozambique to assess genetic, antigenic and antiviral susceptibility profile of influenza virus.

Methods

A subset of samples (n = 20) from influenza positive children detected in two hospitals in Maputo city during 2015 season as part of the implementation of influenza surveillance system, were selected. The following assays were performed on these samples: antigenic characterization by hemagglutination inhibition assay, genetic characterization by Sanger sequencing of hemagglutinin (HA) and neuramin

SUBMITTER: Tivane A 

PROVIDER: S-EPMC6062064 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature