Risk of breast cancer in the UK biobank female cohort and its relationship to anthropometric and reproductive factors.

ABSTRACT:

Background

Anthropometric and reproductive factors have been reported as being established risk factors for breast cancer (BC). This study explores the contribution of anthropometric and reproductive factors in UK females developing BC in a large longitudinal cohort.

Methods

Data from the UK Biobank prospective study of 273,467 UK females were analyzed. Relative risks (RRs) and 95% confidence intervals (CIs) for each factor were adjusted for age, family history of BC and deprivation score. The analyses were stratified by the menopausal status.

Results

Over the 9 years of follow up the total number of BC cases were 14,231 with 3,378 (23.7%) incident cases with an incidence rate of 2.09 per 1000 person-years. In pre-menopausal, increase in age, height, having low BMI, l

SUBMITTER: Al-Ajmi K 

PROVIDER: S-EPMC6062099 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature