Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits.

ABSTRACT: Undoped and Fe-doped ZnO nanoparticles (NPs) were synthesized using Amaranthus spinosus leaf extract as a reducing agent. The physicochemical traits, dissolution, cytotoxicity, as well as the antioxidant, photocatalytic and antibacterial activities of synthesized NPs were investigated. The results revealed that ZnO NPs were rod shaped with hexagonal phase structure, and their crystal size, dissolubility and aggregation decreased with Fe doping of NPs. Cytotoxicity of the NPs was studied against MCF-7 cells by MTT assay. IC₅₀ values for undoped and 1 wt% Fe-doped ZnO NPs were found to be 400 and 600 μg mL^-1, respectively. Cell viability with Fe-doped ZnO NPs was higher than with undoped ZnO. Among the synthesized NPs, A. spinosus-mediated 1 wt% Fe-doped Z

SUBMITTER: Aiswarya Devi S 

PROVIDER: S-EPMC6062353 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature