Accumulation, biotransformation, and multi-biomarker responses after exposure to arsenic species in the earthworm Eisenia fetida.

ABSTRACT: Earthworms (Eisenia fetida) were exposed to OECD soils contaminated with arsenite (29.3 mg kg^-1), arsenate (35.2 mg kg^-1), monomethylarsonate (342.5 mg kg^-1) and dimethylarsinate (373.0 mg kg^-1) for 64 days. The exposure concentration for the four arsenic species was set at one-tenth of 14 d-LC₅₀ in order to compare their toxicity. Eight biomarkers including superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, glutathione reductase, reduced glutathione, lipid peroxidation and metallothioneins were analyzed in the organisms. A multi-biomarker approach, the integrated biomarker response (IBR) index, was adopted to summarize the multi-biomarker responses to a single value, reflecting the integra

SUBMITTER: Wang Z 

PROVIDER: S-EPMC6062360 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature