Lymph Node Radiotherapy Instead of Extended Axillary Surgery - the New Standard?

ABSTRACT: Breast cancer treatment has undergone major changes in the last 20 years. Specifically, the role of axillary lymph node dissection has changed from radical axillary dissection with excision of a high number of lymph nodes to sentinel lymph node biopsy (SLNB). This paradigm shift is associated with a controversial debate regarding the significance of axillary staging, the need for surgery, and the role of radiotherapy. Looking ahead, lymph node staging and axillary treatment might shift from SLNB and/or axillary dissection to ultrasound-guided needle biopsy and irradiation of regional lymph nodes in order to reduce treatment-related sequelae in early-stage breast cancer.

SUBMITTER: Niehoff P 

PROVIDER: S-EPMC6062724 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature