Macrophage Migration Inhibitory Factor -173GC Variant Might Increase the Risk of Behcet's Disease.

ABSTRACT: OBJECTIVE:The aim of the present study was to investigate any possible association between the macrophage migration inhibitory factor (MIF) -173GC variant and Behçet's disease (BD) in a group of Turkish patients. SUBJECTS AND METHODS:A total of 111 patients with BD and 100 healthy controls were enrolled in this study. Genomic DNA was extracted from peripheral lymphocytes. The MIF -173GC variant was genotyped using polymerase chain reaction restriction fragment length polymorphism. The allele and genotype frequencies of patients and controls were compared using the χ2 test. RESULTS:A statistically significant difference in the distribution of the genotype was observed between BD patients and healthy controls. The homo-genotype CC was more prevalent in the patient group compared to the contr

SUBMITTER: Nursal AF 

PROVIDER: S-EPMC6062730 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature