Children with Chronic Disease Bear the Highest Burden of Pediatric Sepsis.

ABSTRACT:

Objective

To describe the contemporary epidemiology of pediatric sepsis in children with chronic disease, and the contribution of chronic diseases to mortality. We examined the incidence and hospital mortality of pediatric sepsis in a nationally representative sample and described the contribution of chronic diseases to hospital mortality.

Study design

We analyzed the 2013 Nationwide Readmissions Database using a retrospective cohort design. We included non-neonatal patients <19 years of age hospitalized with sepsis. We examined patient characteristics, the distribution of chronic disease, and the estimated national incidence, and described hospital mortality. We used mixed effects logistic regression to explore the association between chronic diseases and hospital mortality

SUBMITTER: Prout AJ 

PROVIDER: S-EPMC6063765 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature