Continuous embryo culture elicits higher blastulation but similar cumulative delivery rates than sequential: a large prospective study.

ABSTRACT:

Purpose

To assess whether continuous embryo culture involves better embryological and/or clinical outcomes than sequential.

Methods

Prospective study at a private IVF center. All consecutive IVF cycles (September 2013-2015) fulfilling the inclusion criteria underwent embryo culture in either Continuous-Single-Culture-Media (CSCM, n = 972) or sequential media (Quinn's Advantage, n = 514), respectively. ICSI, blastocyst culture in either standard (MINC) or undisturbed (Embryoscope) incubation, transfer (until September 2016), and pregnancy follow-up (until September 2017) were performed. When aneuploidy testing was required, trophectoderm biopsy and qPCR were performed. Sub-analyses and logistic regression corrected for confounders were performed. The primary outcomes were ove

SUBMITTER: Cimadomo D 

PROVIDER: S-EPMC6063814 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature