MiRNAs regulate acute transcriptional changes in broiler embryos in response to modification of incubation temperature.

ABSTRACT: MicroRNAs are post-transcriptional regulators that play critical roles in diverse biological processes. We hypothesize that miRNAs may be involved in regulating transcriptome responses to changes in embryonic incubation temperature in chickens affecting differentiation and proliferation processes during tissue development. Therefore, we conducted comparative transcriptome profiling of miRNAs to examine altered expression in breast and hind muscle of embryos and day 35 chickens experiencing high (38.8 °C), control (37.8 °C), or low (36.8 °C) embryonic incubation temperature during embryonic day (ED) 7-10 or ED10-13. The results revealed differential expression of miRNAs due to modification of embryonic incubation temperature in a muscle type-specific and a developmental stage-specific manne

SUBMITTER: Naraballobh W 

PROVIDER: S-EPMC6063901 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature