Ontology highlight
ABSTRACT:
SUBMITTER: Zheng Z
PROVIDER: S-EPMC6063995 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Zheng Zhihao Z Lauritzen J Scott JS Perlman Eric E Robinson Camenzind G CG Nichols Matthew M Milkie Daniel D Torrens Omar O Price John J Fisher Corey B CB Sharifi Nadiya N Calle-Schuler Steven A SA Kmecova Lucia L Ali Iqbal J IJ Karsh Bill B Trautman Eric T ET Bogovic John A JA Hanslovsky Philipp P Jefferis Gregory S X E GSXE Kazhdan Michael M Khairy Khaled K Saalfeld Stephan S Fetter Richard D RD Bock Davi D DD
Cell 20180719 3
Drosophila melanogaster has a rich repertoire of innate and learned behaviors. Its 100,000-neuron brain is a large but tractable target for comprehensive neural circuit mapping. Only electron microscopy (EM) enables complete, unbiased mapping of synaptic connectivity; however, the fly brain is too large for conventional EM. We developed a custom high-throughput EM platform and imaged the entire brain of an adult female fly at synaptic resolution. To validate the dataset, we traced brain-spanning ...[more]