Disclosure of amyloid positron emission tomography results to individuals without dementia: a systematic review.

ABSTRACT:

Background

Disclosure of amyloid positron emission tomography (PET) results to individuals without dementia has become standard practice in secondary prevention trials and also increasingly occurs in clinical practice. However, this is controversial given the current lack of understanding of the predictive value of a PET result at the individual level and absence of disease-modifying treatments. In this study, we systematically reviewed the literature on the disclosure of amyloid PET in cognitively normal (CN) individuals and patients with mild cognitive impairment (MCI) in both research and clinical settings.

Methods

We performed a systematic literature search of four scientific databases. Two independent reviewers screened the identified records and selected relevant artic

SUBMITTER: de Wilde A 

PROVIDER: S-EPMC6064628 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature