A descriptive study on selected growth parameters and growth hormone receptor gene in healthy young adults from the American Midwest.

ABSTRACT: CONTEXT:The first study of growth hormone receptor (GHR) genotypes in healthy young adults in the United States attending a Midwestern university and impact on selected growth parameters. OBJECTIVE:To describe the frequency of GHR genotypes in a sample of healthy young adults from the United States attending a university in the Midwest and analyze the relationship between GHR genotypes and selected growth parameters. DESIGN:Saliva was collected from 459 healthy young adults (237 females, 222 males; age range = 18-25 y) and DNA isolated for genotyping of GHR alleles (fl/fl, fl/d3, or d3/d3). Selected growth parameters were collected and GHR genotype data examined for previously reported associations (e.g., height, weight or bone mass density) or novel findings (e.g., % body water and index

SUBMITTER: Hartin SN 

PROVIDER: S-EPMC6064664 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature