Differential Regulation of the Phenazine Biosynthetic Operons by Quorum Sensing in Pseudomonas aeruginosa PAO1-N.

ABSTRACT: The Pseudomonas aeruginosa quorum sensing (QS) network plays a key role in the adaptation to environmental changes and the control of virulence factor production in this opportunistic human pathogen. Three interlinked QS systems, namely las, rhl, and pqs, are central to the production of pyocyanin, a phenazine virulence factor which is typically used as phenotypic marker for analysing QS. Pyocyanin production in P. aeruginosa is a complex process involving two almost identical operons termed phzA₁B₁C₁D₁E₁F₁G₁ (phz1) and phzA₂B₂C₂D₂E₂F

SUBMITTER: Higgins S 

PROVIDER: S-EPMC6064868 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature