Effects of Equol Supplement on Bone and Cardiovascular Parameters in Middle-Aged Japanese Women: A Prospective Observational Study.

ABSTRACT:

Objective

To examine changes in the bone and cardiovascular parameters and tolerability in middle-aged Japanese women taking equol supplement for a year.

Design

This was a prospective observational study.

Subjects and setting

Participants were 74 women receiving outpatient care at Hamasite Medical Clinic, Minato-ku, Tokyo, from 2013 to 2015.

Interventions

Participants received per oral equol-containing supplement, 10 mg/day.

Outcome measures

The primary outcome measures were percent changes in bone and cardiovascular parameters after 1 year supplementation with equol. The secondary measures included factors affecting the parameter changes and adverse effects associated with equol use for a year.

Results

Reduction in arterial stiffness was observed

SUBMITTER: Yoshikata R 

PROVIDER: S-EPMC6065522 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature