Toward the implementation of genomic applications for smoking cessation and smoking-related diseases.

ABSTRACT: The incorporation of genomic information into routine care settings is a burgeoning area for investigation in behavioral medicine. The past decade has witnessed rapid advancements in knowledge of genetic biomarkers associated with smoking behaviors and tobacco-related morbidity and mortality, providing the basis for promising genomic applications in clinical and community settings. We assessed the current state of readiness for implementing genomic applications involving variation in the α5 nicotinic cholinergic receptor subunit gene CHRNA5 and smoking outcomes (behaviors and related diseases) using a process that could be translatable to a wide range of genomic applications in behavioral medicine. We reviewed the scientific literature involving CHRNA5 genetic variation and smoking cessati

SUBMITTER: Ramsey AT 

PROVIDER: S-EPMC6065540 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature