The vaginal eukaryotic DNA virome and preterm birth.

ABSTRACT:

Background

Despite decades of attempts to link infectious agents to preterm birth, an exact causative microbe or community of microbes remains elusive. Culture-independent sequencing of vaginal bacterial communities demonstrates community characteristics are associated with preterm birth, although none are specific enough to apply clinically. Viruses are important components of the vaginal microbiome and have dynamic relationships with vaginal bacterial communities. We hypothesized that vaginal eukaryotic DNA viral communities (the "vaginal virome") either alone or in the context of bacterial communities are associated with preterm birth.

Objective

The objective of this study was to use high-throughput sequencing to examine the vaginal eukaryotic DNA virome in a cohort of pr

SUBMITTER: Wylie KM 

PROVIDER: S-EPMC6066425 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature