Transmissibility of Norovirus in Urban Versus Rural Households in a Large Community Outbreak in China.

ABSTRACT: BACKGROUND:Norovirus is a leading cause of outbreaks of acute infectious gastroenteritis worldwide, yet its transmissibility within households and associated risk factors remain unknown in developing countries. METHODS:Household, demographic, and clinical data were collected from a semi-urban area in south China where an outbreak occurred in the winter of 2014. Using a Bayesian modeling framework, we assessed the transmissibility and potential risk modifiers in both urban and rural households. RESULTS:In urban apartment buildings, the secondary attack rates were 84% (95% credible interval [CI] = 60%, 96%) among households of size two and 29% (95% CI = 9.6%, 53%) in larger households. In the rural village, secondary attack rate estimates were lower than the urban setting, 13% (0.51%, 54%) f

SUBMITTER: Tsang TK 

PROVIDER: S-EPMC6066449 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature