Mortality and Associated Morbidities Following Traumatic Brain Injury in Older Medicare Statin Users.

ABSTRACT:

Objective

To assess the relationship between posttraumatic brain injury statin use and (1) mortality and (2) the incidence of associated morbidities, including stroke, depression, and Alzheimer's disease and related dementias following injury.

Setting and participants

Nested cohort of all Medicare beneficiaries 65 years of age and older who survived a traumatic brain injury (TBI) hospitalization during 2006 through 2010. The final sample comprised 100 515 beneficiaries.

Design

Retrospective cohort study of older Medicare beneficiaries. Relative risks (RR) and 95% confidence interval (CI) were obtained using discrete time analysis and generalized estimating equations.

Measures

The exposure of interest included monthly atorvastatin, fluvastatin, lovastatin, prava

SUBMITTER: Khokhar B 

PROVIDER: S-EPMC6066463 | biostudies-literature | 2018 Nov/Dec

REPOSITORIES: biostudies-literature