Characterization of Mucus-Related Properties of Streptococcus thermophilus: From Adhesion to Induction.

ABSTRACT: Mucus is a major component of the intestinal barrier involved both in the protection of the host and the fitness of commensals of the gut. Streptococcus thermophilus is consumed world-wide in fermented dairy products and is also recognized as a probiotic, as its consumption is associated with improved lactose digestion. We determined the overall effect of S. thermophilus on the mucus by evaluating its ability to adhere, degrade, modify, or induce the production of mucus and/or mucins. Adhesion was analyzed in vitro using two types of mucins (from pig or human biopsies) and mucus-producing intestinal HT29-MTX cells. The induction of mucus was characterized in two different rodent models, in which S. thermophilus is the unique bacterial species in the digestive tr

SUBMITTER: Fernandez N 

PROVIDER: S-EPMC6067005 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature