Symptomatic Course of Foot Osteoarthritis Phenotypes: An 18-Month Prospective Analysis of Community-Dwelling Older Adults.

ABSTRACT:

Objective

Osteoarthritis (OA) is a heterogeneous disease, and symptom progression at the foot is unclear. This study investigated the symptomatic course of 3 predefined foot OA phenotypes over an 18-month period.

Methods

The Clinical Assessment Study of the Foot is a community-based cohort of adults ages ≥50 years in North Staffordshire, UK. Participants who reported foot pain in a postal health survey and underwent radiographic assessment were mailed an 18-month followup survey. Changes in descriptive and symptomatic outcomes over 18 months were compared across the 3 phenotypes to determine within-phenotype changes and between-phenotype differences.

Results

Of 533 participants at baseline, 478 (89.7%) responded at 18 months. All 3 phenotypes showed small within-pheno

SUBMITTER: Downes TJ 

PROVIDER: S-EPMC6067068 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature